Medication-Assisted Treatment

Medication-Assisted Treatment (MAT) is the use of medications, in combination with other therapies, to provide a whole-patient approach to the treatment of substance use disorders. Examples of medications are methadone and buprenorphine for opioid addiction; naltrexone and acamprosate for alcohol addiction; and nicotine replacement therapy for tobacco smokers who are addicted to nicotine. Medications and counseling are the standard of care for a number of substance use disorders, including tobacco use disorders, alcohol use disorders, and opioid use disorders.

Individuals who are in Medication-Assisted Treatment should be aware of their rights under Federal anti-discrimination laws. Please feel free to share this information with family, friends and advocates. Learn about your rights here.

What is Methadone?

Methadone works by changing how the brain and nervous system respond to pain. It lessens the painful symptoms of opiate withdrawal and blocks the euphoric effects of opiate drugs such as heroin, morphine, and codeine, as well as semi-synthetic opioids like oxycodone and hydrocodone. Women who are pregnant or breastfeeding can safely take methadone.

What is Buprenorphine?

Buprenorphine is an opioid partial agonist. This means that, like opioids, it produces effects such as euphoria or respiratory depression. With buprenorphine, however, these effects are weaker than those of full drugs such as heroin and methadone. Limited information exists on the use of buprenorphine in women who are pregnant and have an opioid dependency.

What is Naltrexone?

Naltrexone blocks the euphoric and sedative effects of drugs such as heroin, morphine, and codeine. It works differently in the body than buprenorphine and methadone, which activate opioid receptors in the body that suppress cravings. Naltrexone binds and blocks opioid receptors and is reported to reduce opioid cravings. There is no abuse and diversion potential with naltrexone.

For more information

Buprenorphine Practitioner Locator

Opioid Treatment Program Directory

Vivitrol Treatment Provider


Rhode Island Medication-Assisted Treatment Services

Addiction Recovery Institute RI



31 North Union Street

Pawtucket, RI 02860

(401) 725-2520


205 Hallene Road, Suite 102

Warwick, RI 02886

(401) 737-4788

CODAC Behavioral Healthcare


CODAC Cranston

1052 Park Avenue, Cranston, RI 02910

(401) 461-5056

CODAC Providence

349 Huntington Avenue, Providence, RI 02909

(401) 942-1450

CODAC Newport

93 Thames Street, Newport, RI 02840

(401) 846-4150

CODAC South County

350 Columbia Street, Wakefield, RI 02879

(401) 789-0934

CODAC East Bay

850 Waterman Avenue, East Providence, RI 02914

(401) 434-4999

Center for Treatment & Recovery


82 Pond Street, Pawtucket, RI 02860

(401) 727-1287

Discovery House


66 Pavilion Avenue, Providence, RI, 02905

(877) 827-5042

1625 Diamond Hill Road, Woonsocket, RI 02895

(877) 785-5902

BHG Providence Treatment Center


160 Narragansett Avenue, Providence, RI 02907

(401) 941-4488

Toll Free: (844) 535-7291